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Simultaneous Visualization of Both Signaling Cascade Activity and End-Point Gene Expression in Single Cells

We have developed an approach for simultaneous detection of individual endogenous protein modifications and mRNA molecules in single cells in situ. For this purpose we combined two methods previously developed in our lab: in situ proximity ligation assay for the detection of individual protein inter...

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Hlavní autoři: Weibrecht, Irene, Grundberg, Ida, Nilsson, Mats, Söderberg, Ola
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102075/
https://ncbi.nlm.nih.gov/pubmed/21647446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020148
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