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Two types of chloride transporters are required for GABA(A) receptor-mediated inhibition in C. elegans

Chloride influx through GABA-gated Cl(−) channels, the principal mechanism for inhibiting neural activity in the brain, requires a Cl(−) gradient established in part by K(+)–Cl(−) cotransporters (KCCs). We screened for Caenorhabditis elegans mutants defective for inhibitory neurotransmission and ide...

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Detalhes bibliográficos
Main Authors: Bellemer, Andrew, Hirata, Taku, Romero, Michael F, Koelle, Michael R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101993/
https://ncbi.nlm.nih.gov/pubmed/21427702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.83
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