Fungicidal Activity of Fluconazole against Candida albicans in a Synthetic Vagina-Simulative Medium

Fluconazole (FLZ) has emerged as a highly successful agent in the management of systemic infections of Candida. Cure rates for symptomatic candidiasis following single 150-mg FLZ dose therapy exceed 90%. In vitro, however, FLZ is fungistatic only in a narrow pH range and is not effective at vaginal...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Moosa, Mahomed-Yunus S., Sobel, Jack D., Elhalis, Hussain, Du, Wenjin, Akins, Robert A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Susceptibility
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310176/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14693534/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.1.161-167.2004
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