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Efficacy of BB-83698, a Novel Peptide Deformylase Inhibitor, in a Mouse Model of Pneumococcal Pneumonia

The efficacy of BB-83698, a novel potent peptide deformylase inhibitor, was evaluated in a mouse model of acute pneumonia. The Streptococcus pneumoniae isolates tested included four virulent strains (one penicillin-susceptible wild-type strain, one macrolide-resistant strain, and two quinolone-resis...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Azoulay-Dupuis, E., Mohler, J., Bédos, J. P.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310171/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14693522/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.1.80-85.2004
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