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Integrin-Linked Kinase Regulates Integrin Signaling in Human Trabecular Meshwork Cells

PURPOSE. To determine whether integrin-linked kinase (ILK) controls the organization of the actin cytoskeleton in the trabecular meshwork (TM) by regulating integrin co-signaling. METHODS. The cell binding domain and the Heparin II (Hep II) domain of fibronectin were used to activate α5β1 and α4β1 i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Faralli, Jennifer A., Newman, Jessica R., Sheibani, Nader, Dedhar, Shoukat, Peters, Donna M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Association for Research in Vision and Ophthalmology, Inc. 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101682/
https://ncbi.nlm.nih.gov/pubmed/21071740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6397
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