Upregulation of Mouse Genes in HSV-1 Latent TG after Butyrate Treatment Implicates the Multiple Roles of the LAT-ICP0 Locus

PURPOSE. To determine host response by gene expression in HSV-1 latent trigeminal ganglia (TG) after sodium butyrate (NaBu) treatment. METHODS. Corneas of 6-week-old female BALB/c mice were scarified and inoculated with HSV-1 17Syn(+) (high phenotypic reactivator) or its mutant 17ΔPst(LAT(−)) (low p...

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Main Authors: Clement, Christian, Bhattacharjee, Partha S., Kumar, Manish, Foster, Timothy P., Thompson, Hilary W., Hill, James M.
Format: Artigo
Language:Inglês
Published: Association for Research in Vision and Ophthalmology, Inc. 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101669/
https://ncbi.nlm.nih.gov/pubmed/20881297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-5019
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