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Dark Matters in AMD Genetics: Epigenetics and Stochasticity

Missing heritability in the study of complex disease has been called dark matter. This review enlarges the scope of this term to include epigenetics and stochasticity, nongenetic sources of risk in complex diseases such as age-related macular degeneration.

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Detalhes bibliográficos
Autor principal: Hjelmeland, Leonard M.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101660/
https://ncbi.nlm.nih.gov/pubmed/21429863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6765
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