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Modeling Antibiotic Tolerance in Biofilms by Accounting for Nutrient Limitation

A mathematical model of biofilm dynamics was used to investigate the protection from antibiotic killing that can be afforded to microorganisms in biofilms based on a mechanism of localized nutrient limitation and slow growth. The model assumed that the rate of killing by the antibiotic was directly...

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Bibliografiske detaljer
Main Authors: Roberts, Mark E., Stewart, Philip S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC310152/
https://ncbi.nlm.nih.gov/pubmed/14693517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.1.48-52.2004
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