Effects of Chronic Antagonism of Endocannabinoid-1 Receptors on Glucose Tolerance and Insulin Action in Skeletal Muscles of Lean and Obese Zucker Rats

BACKGROUND/AIMS: Antagonism of the endocannabinoid receptor-1 (CB1R) directly improves whole-body metabolic parameters of insulin resistance. The present investigation determined the effects of chronic CB1R antagonism on whole-body and skeletal-muscle insulin action in insulin-sensitive lean and ins...

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Autores principales: Lindborg, Katherine A., Jacob, Stephan, Henriksen, Erik J.
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2011
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Original Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101519/
https://ncbi.nlm.nih.gov/pubmed/22258464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000322826
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