A Novel Gene Cassette, aacA43, in a Plasmid-Borne Class 1 Integron

A novel gene cassette, aacA43, was identified in the aadB-aacA43-oxa10-smr2 cassette array in a class 1 integron. Like related aminoglycoside-(6′)-acetyltransferases, AacA43 confers clinically relevant resistance to kanamycin, tobramycin, and some less-used aminoglycosides but not to gentamicin. Alt...

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Autors principals: Partridge, Sally R., Thomas, Lee C., Ginn, Andrew N., Wiklendt, Agnieszka M., Kyme, Pierre, Iredell, Jonathan R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101451/
https://ncbi.nlm.nih.gov/pubmed/21422220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01582-10
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