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Induction of Antimalaria Immunity by Pyrimethamine Prophylaxis during Exposure to Sporozoites Is Curtailed by Parasite Resistance

Each year, infections with the protozoan parasite Plasmodium falciparum kill 1 million people, mostly children in Africa. Intermittent preventive treatment (IPT) with sulfadoxine-pyrimethamine (SP) reduces the incidence of malaria and aims to prevent mortality in infants, children, and pregnant wome...

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Detalhes bibliográficos
Main Authors: Friesen, Johannes, Borrmann, Steffen, Matuschewski, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101443/
https://ncbi.nlm.nih.gov/pubmed/21444698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01717-10
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