Artesunate Tolerance in Transgenic Plasmodium falciparum Parasites Overexpressing a Tryptophan-Rich Protein

Due to their rapid, potent action on young and mature intraerythrocytic stages, artemisinin derivatives are central to drug combination therapies for Plasmodium falciparum malaria. However, the evidence for emerging parasite resistance/tolerance to artemisinins in southeast Asia is of great concern....

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Détails bibliographiques
Auteurs principaux: Deplaine, Guillaume, Lavazec, Catherine, Bischoff, Emmanuel, Natalang, Onguma, Perrot, Sylvie, Guillotte-Blisnick, Micheline, Coppée, Jean-Yves, Pradines, Bruno, Mercereau-Puijalon, Odile, David, Peter H.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
Sujets:
Mechanisms of Resistance
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101408/
https://ncbi.nlm.nih.gov/pubmed/21464256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01409-10
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