Synergistic Effect of 14-Alpha-Lipoyl Andrographolide and Various Antibiotics on the Formation of Biofilms and Production of Exopolysaccharide and Pyocyanin by Pseudomonas aeruginosa

Pseudomonas aeruginosa produces a biofilm that provides the bacteria with an effective barrier against antibiotics. Here, we investigated the synergy of various antibiotics with 14-alpha-lipoyl andrographolide (AL-1), focusing upon synthesis of the biofilm. AL-1 also inhibited the production of the...

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Библиографические подробности
Главные авторы: Zeng, Xiangping, Liu, Xiangyang, Bian, Jiang, Pei, Gang, Dai, Huanqin, Polyak, Steven W., Song, Fuhang, Ma, Li, Wang, Yuqiang, Zhang, Lixin
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2011
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Mechanisms of Action: Physiological Effects
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101388/
https://ncbi.nlm.nih.gov/pubmed/21422201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00575-10
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