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Paraoxonase 1 (PON1) Polymorphisms, Haplotypes and Activity in Predicting CAD Risk in North-West Indian Punjabis

BACKGROUND: Human serum paraoxonase-1 (PON1) prevents oxidation of low density lipoprotein cholesterol (LDL-C) and hydrolyzes the oxidized form, therefore preventing the development of atherosclerosis. The polymorphisms of PON1 gene are known to affect the PON1 activity and thereby coronary artery d...

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Detalhes bibliográficos
Main Authors: Gupta, Nidhi, Singh, Surjit, Maturu, V. Nagarjuna, Sharma, Yash Paul, Gill, Kiran Dip
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101202/
https://ncbi.nlm.nih.gov/pubmed/21629682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017805
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