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Positive selection in the hemagglutinin-neuraminidase gene of Newcastle disease virus and its effect on vaccine efficacy

BACKGROUND: To investigate the relationship between the selective pressure and the sequence variation of the hemagglutinin-neuraminidase (HN) protein, we performed the positive selection analysis by estimating the ratio of non-synonymous to synonymous substitutions with 132 complete HN gene sequence...

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Detalhes bibliográficos
Main Authors: Gu, Min, Liu, Wujie, Xu, Lijun, Cao, Yongzhong, Yao, Chunfeng, Hu, Shunlin, Liu, Xiufan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101160/
https://ncbi.nlm.nih.gov/pubmed/21453506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-150
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