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Mapping the Reaction Coordinates of Enzymatic Defluorination
The carbon-fluorine bond is the strongest covalent bond in organic chemistry, yet fluoroacetate dehalogenases can readily hydrolyze this bond under mild physiological conditions. Elucidating the molecular basis of this rare biocatalytic activity will provide the fundamental chemical insights of how...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3101105/ https://ncbi.nlm.nih.gov/pubmed/21510690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja200277d |
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