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Clustering heterochromatin: Sir3 promotes telomere clustering independently of silencing in yeast

A general feature of the nucleus is the organization of repetitive deoxyribonucleic acid sequences in clusters concentrating silencing factors. In budding yeast, we investigated how telomeres cluster in perinuclear foci associated with the silencing complex Sir2–Sir3–Sir4 and found that Sir3 is limi...

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Autori principali: Ruault, Myriam, De Meyer, Arnaud, Loïodice, Isabelle, Taddei, Angela
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101097/
https://ncbi.nlm.nih.gov/pubmed/21300849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201008007
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