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Barth syndrome mutations that cause tafazzin complex lability

Deficits in mitochondrial function result in many human diseases. The X-linked disease Barth syndrome (BTHS) is caused by mutations in the tafazzin gene TAZ1. Its product, Taz1p, participates in the metabolism of cardiolipin, the signature phospholipid of mitochondria. In this paper, a yeast BTHS mu...

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Autors principals: Claypool, Steven M., Whited, Kevin, Srijumnong, Santi, Han, Xianlin, Koehler, Carla M.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101092/
https://ncbi.nlm.nih.gov/pubmed/21300850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201008177
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