A novel role for BRCA1 in regulating breast cancer cell spreading and motility

BRCA1 C-terminal (BRCT) domains in BRCA1 are essential for tumor suppressor function, though the underlying mechanisms remain unclear. We identified ezrin, radixin, and moesin as BRCA1 BRCT domain–interacting proteins. Ezrin–radixin–moesin (ERM) and F-actin colocalized with BRCA1 at the plasma membr...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Coene, Elisabeth D., Gadelha, Catarina, White, Nicholas, Malhas, Ashraf, Thomas, Benjamin, Shaw, Michael, Vaux, David J.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2011
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101087/
https://ncbi.nlm.nih.gov/pubmed/21282464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201004136
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares