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C-Jun NH(2)-Terminal Kinase Contributes to Dexmedetomidine-Induced Contraction in Isolated Rat Aortic Smooth Muscle
PURPOSE: Dexmedetomidine, a full agonist of α(2B)-adrenoceptors, is used for analgesia and sedation in the intensive care units. Dexmedetomidine produces an initial transient hypertension due to the activation of post-junctional α(2B)-adrenoceptors on vascular smooth muscle cells (SMCs). The aims of...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Yonsei University College of Medicine
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3101051/ https://ncbi.nlm.nih.gov/pubmed/21488184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2011.52.3.420 |
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