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Native Low-Density Lipoprotein-Dependent Interleukin-8 Production Through Pertussis Toxin-Sensitive G-Protein Coupled Receptors and Hydrogen Peroxide Generation Contributes to Migration of Human Aortic Smooth Muscle Cells

PURPOSE: Stimulation of human aortic smooth muscle cells (hAoSMCs) with native low-density lipoprotein (nLDL) induced the production of interleukin-8 (IL-8) that is involved in the pathogenesis of cardiovascular diseases. However, the process of signal transduction of nLDL was currently uncharacteri...

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Détails bibliographiques
Auteurs principaux: Lim, Hyun Kyo, Ryoo, Sungwoo
Format: Artigo
Langue:Inglês
Publié: Yonsei University College of Medicine 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101039/
https://ncbi.nlm.nih.gov/pubmed/21488183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2011.52.3.413
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