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Thymosin β(4) inhibits TNF-α-induced NF-κB activation, IL-8 expression, and the sensitizing effects by its partners PINCH-1 and ILK

The mechanisms by which thymosin β 4 (Tβ(4)) regulates the inflammatory response to injury are poorly understood. Previously, we demonstrated that ectopic Tβ(4) treatment inhibits injury-induced proinflammatory cytokine and chemokine production. We have also shown that Tβ(4) suppresses TNF-α-mediate...

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Detalhes bibliográficos
Main Authors: Qiu, Ping, Wheater, Michelle Kurpakus, Qiu, Yue, Sosne, Gabriel
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101037/
https://ncbi.nlm.nih.gov/pubmed/21343177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-167940
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