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Solid-state (2)H NMR relaxation illuminates functional dynamics of retinal cofactor in membrane activation of rhodopsin

Rhodopsin is a canonical member of the family of G protein-coupled receptors, which transmit signals across cellular membranes and are linked to many drug interventions in humans. Here we show that solid-state (2)H NMR relaxation allows investigation of light-induced changes in local ps–ns time scal...

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書目詳細資料
Main Authors: Struts, Andrey V., Salgado, Gilmar F. J., Brown, Michael F.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100945/
https://ncbi.nlm.nih.gov/pubmed/21527723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014692108
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