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Caenorhabditis elegans chromatin-associated proteins SET-2 and ASH-2 are differentially required for histone H3 Lys 4 methylation in embryos and adult germ cells

Methylation of histone H3 lysine 4 (H3K4me), a mark associated with gene activation, is mediated by SET1 and the related mixed lineage leukemia (MLL) histone methyltransferases (HMTs) across species. Mammals contain seven H3K4 HMTs, Set1A, Set1B, and MLL1–MLL5. The activity of SET1 and MLL proteins...

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Detalhes bibliográficos
Main Authors: Xiao, Yu, Bedet, Cécile, Robert, Valérie J. P., Simonet, Thomas, Dunkelbarger, Steve, Rakotomalala, Cédric, Soete, Gwen, Korswagen, Hendrik C., Strome, Susan, Palladino, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100940/
https://ncbi.nlm.nih.gov/pubmed/21527717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019290108
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