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Alteration of Hepatic but Not Renal Transporter Expression in Diet-Induced Obese Mice
Drug pharmacokinetics can be altered in obese and diabetic subjects. In consideration of the prevalence of obesity and diabetes, characterization of transporter expression in mouse models of diabetes and obesity may be a useful tool to aid in prediction of altered drug pharmacokinetics or adverse dr...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The American Society for Pharmacology and Experimental Therapeutics
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100907/ https://ncbi.nlm.nih.gov/pubmed/21430232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.110.037507 |
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