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Computational Prediction of O-linked Glycosylation Sites That Preferentially Map on Intrinsically Disordered Regions of Extracellular Proteins

O-glycosylation of mammalian proteins is one of the important posttranslational modifications. We applied a support vector machine (SVM) to predict whether Ser or Thr is glycosylated, in order to elucidate the O-glycosylation mechanism. O-glycosylated sites were often found clustered along the seque...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nishikawa, Ikuko, Nakajima, Yukiko, Ito, Masahiro, Fukuchi, Satoshi, Homma, Keiichi, Nishikawa, Ken
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Diversity Preservation International (MDPI) 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100847/
https://ncbi.nlm.nih.gov/pubmed/21614187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms11124991
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