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Computer-Based De Novo Designs of Tripeptides as Novel Neuraminidase Inhibitors

The latest influenza A (H1N1) pandemic attracted worldwide attention and called for the urgent development of novel antiviral drugs. Here, seven tripeptides are designed and explored as neuraminidase (NA) inhibitors on the structural basis of known inhibitors. Their interactions with NA are studied...

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Detalhes bibliográficos
Main Authors: Yang, Zhiwei, Yang, Gang, Zu, Yuangang, Fu, Yujie, Zhou, Lijun
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100827/
https://ncbi.nlm.nih.gov/pubmed/21614183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms11124932
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