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Down-Regulation of Hypothalamic Corticotropin-Releasing Hormone Messenger Ribonucleic Acid (mRNA) Precedes Early-Life Experience-Induced Changes in Hippocampal Glucocorticoid Receptor mRNA

Early-life experiences, including maternal interaction, profoundly influence hormonal stress responses during adulthood. In rats, daily handling during a critical neonatal period leads to a significant and permanent modulation of key molecules that govern hormonal secretion in response to stress. Th...

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Bibliographic Details
Main Authors: AVISHAI-ELINER, SARIT, EGHBAL-AHMADI, MARIAM, TABACHNIK, ELVAN, BRUNSON, KRISTEN L., BARAM, TALLIE Z.
Format: Artigo
Language:Inglês
Published: 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100725/
https://ncbi.nlm.nih.gov/pubmed/11145570
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