Evidence of canonical somatic hypermutation in hairy cell leukemia

To compare hairy cell leukemia (HCL) with chronic lymphocytic leukemia (CLL) and normal B cells with respect to their B-cell receptors, somatic hypermutation (SHM) features in HCL were examined in a series of 130 immunoglobulin gene heavy chain rearrangements, including 102 from 100 classic (HCLc) a...

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Bibliographic Details
Main Authors: Arons, Evgeny, Roth, Laura, Sapolsky, Jeffrey, Suntum, Tara, Stetler-Stevenson, Maryalice, Kreitman, Robert J.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2011
Subjects:
Lymphoid Neoplasia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100693/
https://ncbi.nlm.nih.gov/pubmed/21368287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-316737
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