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Trypanosoma brucei minicircles encode multiple guide RNAs which can direct editing of extensively overlapping sequences.

Small guide RNAs (gRNAs) may direct RNA editing in kinetoplastid mitochondria. We have characterized multiple gRNA genes from Trypanosoma brucei (EATRO 164), that can specify up to 30% of the editing of the COIII, ND7, ND8, and A6 mRNAs and we have also found that the non-translated region of edited...

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Main Authors: Corell, R A, Feagin, J E, Riley, G R, Strickland, T, Guderian, J A, Myler, P J, Stuart, K
Formato: Artigo
Idioma:Inglês
Publicado: 1993
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC310066/
https://ncbi.nlm.nih.gov/pubmed/8414987
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