Ligand-Dependent Mechanisms of sst2A Receptor Trafficking: Role of Site-Specific Phosphorylation and Receptor Activation in the Actions of Biased Somatostatin Agonists

The somatostatin receptor subtype 2A (sst2A) mediates many of somatostatin's neuroendocrine actions and is the primary therapeutic target for the stable somatostatin analogs used to inhibit hormone secretion by pituitary and gastroenteropancreatic tumors. Two new multireceptor targeting somatos...

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Main Authors: Kao, Yachu J., Ghosh, Madhumita, Schonbrunn, Agnes
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2011
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100600/
https://ncbi.nlm.nih.gov/pubmed/21493671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0398
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