Self-Renewal Signalling in Presenescent Tetraploid IMR90 Cells

Endopolyploidy and genomic instability are shared features of both stress-induced cellular senescence and malignant growth. Here, we examined these facets in the widely used normal human fibroblast model of senescence, IMR90. At the presenescence stage, a small (2–7%) proportion of cells overcome th...

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Bibliografiska uppgifter
Huvudupphovsmän: Huna, Anda, Salmina, Kristine, Jascenko, Elina, Duburs, Gunars, Inashkina, Inna, Erenpreisa, Jekaterina
Materialtyp: Artigo
Språk:Inglês
Publicerad: SAGE-Hindawi Access to Research 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100543/
https://ncbi.nlm.nih.gov/pubmed/21629737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/103253
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