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The requirement for the Dam1 complex is dependent upon the number of kinetochore proteins and microtubules

The Dam1 complex attaches the kinetochore to spindle microtubules and is a processivity factor in vitro [1, 2]. In Saccharomyces cerevisiae, which has point centromeres that attach to a single microtubule, deletion of any Dam1 complex member results in chromosome segregation failures and cell death...

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Main Authors: Burrack, Laura S., Applen, Shelly E., Berman, Judith
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100407/
https://ncbi.nlm.nih.gov/pubmed/21549601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.04.002
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