Concentration Independent Modulation of Local Micromechanics in a Fibrin Gel

Methods for tuning extracellular matrix (ECM) mechanics in 3D cell culture that rely on increasing the concentration of either protein or cross-linking molecules fail to control important parameters such as pore size, ligand density, and molecular diffusivity. Alternatively, ECM stiffness can be mod...

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Main Authors: Kotlarchyk, Maxwell A., Shreim, Samir G., Alvarez-Elizondo, Martha B., Estrada, Laura C., Singh, Rahul, Valdevit, Lorenzo, Kniazeva, Ekaterina, Gratton, Enrico, Putnam, Andrew J., Botvinick, Elliot L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100350/
https://ncbi.nlm.nih.gov/pubmed/21629793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020201
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