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Mouse Transgenesis Identifies Conserved Functional Enhancers and cis-Regulatory Motif in the Vertebrate LIM Homeobox Gene Lhx2 Locus

The vertebrate Lhx2 is a member of the LIM homeobox family of transcription factors. It is essential for the normal development of the forebrain, eye, olfactory system and liver as well for the differentiation of lymphoid cells. However, despite the highly restricted spatio-temporal expression patte...

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Detalhes bibliográficos
Main Authors: Lee, Alison P., Brenner, Sydney, Venkatesh, Byrappa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100342/
https://ncbi.nlm.nih.gov/pubmed/21629789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020088
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