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PTHrP Induces Autocrine/Paracrine Proliferation of Bone Tumor Cells through Inhibition of Apoptosis

Giant Cell Tumor of Bone (GCT) is an aggressive skeletal tumor characterized by local bone destruction, high recurrence rates and metastatic potential. Previous work in our lab has shown that the neoplastic cell of GCT is a proliferating pre-osteoblastic stromal cell in which the transcription facto...

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書誌詳細
主要な著者: Mak, Isabella W. Y., Cowan, Robert W., Turcotte, Robert E., Singh, Gurmit, Ghert, Michelle
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100318/
https://ncbi.nlm.nih.gov/pubmed/21625386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019975
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