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Generation of Recombinant Guinea Pig Antibody Fragments to the Human GABA(C) Receptor

To generate monoclonal antibodies to the human ρ1 GABA(C) receptor, a ligand-gated chloride ion channel that is activated by the neurotransmitter γ-aminobutyric acid (GABA), we recovered the immunoglobulin variable heavy chain (V(H)) and light chain (V(L)) regions of a guinea pig immunized with a 14...

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Detalhes bibliográficos
Main Authors: Memic, Adnan, Volgina, Veronica V., Gussin, Hélène A., Pepperberg, David R., Kay, Brian K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100176/
https://ncbi.nlm.nih.gov/pubmed/21362428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2011.02.010
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