Sequence-specific transactivators counteract topoisomerase II-mediated inhibition of in vitro transcription by RNA polymerases I and II.

An inhibitor of RNA polymerase II transcription in vitro has been purified from HeLa cell nuclear extracts. Partial amino acid sequences derived from the purified protein revealed that the inhibitor of transcription corresponded to human topoisomerase II. Order of addition experiments provided evide...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Brou, C, Kuhn, A, Staub, A, Chaudhary, S, Grummt, I, Davidson, I, Tora, L
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 1993
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309990/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8396762/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.17.4011
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