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Construction of Otherwise Isogenic Serotype 6B, 7F, 14, and 19F Capsular Variants of Streptococcus pneumoniae Strain TIGR4

The polysaccharide capsule is the primary virulence factor in Streptococcus pneumoniae. There are at least 90 serotypes of S. pneumoniae, identified based on the immunogenicity of different capsular sugars. The aim of this study was to construct pneumococcal strains that are isogenic except for caps...

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Autori principali: Trzcinski, Krzysztof, Thompson, Claudette M., Lipsitch, Marc
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC309976/
https://ncbi.nlm.nih.gov/pubmed/14660386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.69.12.7364-7370.2003
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