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Mahoganoid and Mahogany Mutations Rectify the Obesity of the Yellow Mouse by Effects on Endosomal Traffic of MC4R Protein

The ubiquitous overexpression of agouti-signaling protein (ASP), a paracrine-signaling molecule that regulates pigment-type switching in the hair follicle of the mouse, is responsible for the obesity and yellow pelage of the Yellow mouse (A(y)). Mahogany (Attractin, Atrn/mg) and mahoganoid (Mahoguni...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Overton, John D., Leibel, Rudolph L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099707/
https://ncbi.nlm.nih.gov/pubmed/21460229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.224592
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