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Glutamate transporter type 3 knockout reduces brain tolerance to focal brain ischemia in mice
Excitatory amino-acid transporters (EAATs) transport glutamate into cells under physiologic conditions. Excitatory amino-acid transporter type 3 (EAAT3) is the major neuronal EAAT and also uptakes cysteine, the rate-limiting substrate for synthesis of glutathione. Thus, we hypothesize that EAAT3 con...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3099634/ https://ncbi.nlm.nih.gov/pubmed/21139629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.222 |
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