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Function and Regulation of Retinoic Acid-Inducible Gene-I

Antiviral innate immunity is triggered by sensing viral nucleic acids. RIG-I (retinoic acid-inducible gene-I) is an intracellular molecule that responds to viral nucleic acids and activates downstream signaling, resulting in the induction of members of the type I interferon (IFN) family, which are r...

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Bibliographic Details
Main Authors: Matsumiya, Tomoh, Stafforini, Diana M.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099591/
https://ncbi.nlm.nih.gov/pubmed/21175414
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