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CRP Polarizes Human Macrophages to a M1 Phenotype and Inhibits Transformation to the M2 Phenotype
OBJECTIVE: Inflammation is pivotal in atherosclerosis. Monocyte-macrophages are crucial in atherosclerosis. Monocytes can develop into subsets: classically (M1) or alternatively (M2) activated cells. Several studies point to a pro-inflammatory role for C-reactive protein (CRP). Since there is a pauc...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3099471/ https://ncbi.nlm.nih.gov/pubmed/21415385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.225508 |
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