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Molecular Targeting of Neural Cancer Stem Cells: TTAGGG, You're It!: Commentary on Castelo-Branco et al

Telomerase is an important mechanism by which cancers escape replicative senescence. In neural tumors, cancer stem cells express telomerase suggesting that this may explain their preferential tumorigenesis. Oligonucleotide telomerase targeting selectively disrupts cancer stem cell growth through the...

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Main Authors: Hjelmeland, Anita B., Rich, Jeremy N.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099413/
https://ncbi.nlm.nih.gov/pubmed/21208901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2686
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