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Resveratrol Metabolites Do Not Elicit Early Pro-apoptotic Mechanisms in Neuroblastoma Cells

Resveratrol, a non-toxic polyphenol, has been shown to inhibit tumor growth in a xenograft mouse model of neuroblasoma. However, resveratrol is rapidly metabolized, mainly to its glucuronidated and sulfated derivatives. In this study we demonstrate that resveratrol alone, and not the glucuronidated...

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Detalhes bibliográficos
Main Authors: Kenealey, Jason D., Subramanian, Lalita, Van Ginkel, Paul R., Darjatmoko, Soesiawati, Lindstrom, Mary J., Somoza, Veronika, Ghosh, Sunil K., Song, Zhenlei, Hsung, Richard P., Kwon, Glen S., Eliceiri, Kevin W., Albert, Daniel M., Polans, Arthur S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099401/
https://ncbi.nlm.nih.gov/pubmed/21401048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jf104901g
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