A new topical formulation enhances relative diclofenac bioavailability in healthy male subjects

AIMS: To evaluate the relative plasma and tissue availability of diclofenac after repeated topical administration of a novel diclofenac acid-based delivery system under development (DCF100C). METHODS: This was a single-centre, open-label, three-period, crossover clinical trial of five discrete diclo...

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Detalhes bibliográficos
Main Authors: Brunner, Martin, Davies, David, Martin, Wolfgang, Leuratti, Chiara, Lackner, Edith, Müller, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Clinical Trials
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099372/
https://ncbi.nlm.nih.gov/pubmed/21241352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.03914.x
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