Blocking Effects of Human Tau on Squid Giant Synapse Transmission and Its Prevention by T-817 MA

Filamentous tau inclusions are hallmarks of Alzheimer's disease and related neurodegenerative tauopathies, but the molecular mechanisms involved in tau-mediated changes in neuronal function and their possible effects on synaptic transmission are unknown. We have evaluated the effects of human t...

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Main Authors: Moreno, Herman, Choi, Soonwook, Yu, Eunah, Brusco, Janaina, Avila, Jesus, Moreira, Jorge E., Sugimori, Mutsuyuki, Llinás, Rodolfo R.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Research Foundation 2011
Teme:
Neuroscience
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099362/
https://ncbi.nlm.nih.gov/pubmed/21629767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2011.00003
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