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Cellular elements of the subarachnoid space promote ALL survival during chemotherapy

CNS infiltration by leukemic cells remains a problematic disease manifestation of acute lymphoblastic leukemia (ALL). Prophylactic regimens for CNS leukemia including intrathecal chemotherapeutics have decreased CNS involvement in ALL, but are not without toxicities. Using co-culture models, we show...

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Detalhes bibliográficos
Main Authors: Akers, Stephen M., Rellick, Stephanie L., Fortney, James E., Gibson, Laura F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099259/
https://ncbi.nlm.nih.gov/pubmed/21269691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2010.12.031
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