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Buffering and the evolution of chromosome-wide gene regulation

Copy number variation (CNV) in terms of aneuploidies of both entire chromosomes and chromosomal segments is an important evolutionary driving force, but it is inevitably accompanied by potentially problematic variations in gene doses and genomic instability. Thus, a delicate balance must be maintain...

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Bibliografiske detaljer
Main Authors: Stenberg, Per, Larsson, Jan
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098985/
https://ncbi.nlm.nih.gov/pubmed/21505791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-011-0319-8
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