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Leptin Enhances NMDA-Induced Spinal Excitation in Rats: A Functional Link between Adipocytokine and Neuropathic Pain

Recent studies have shown that leptin (an adipocytokine) played an important role in nociceptive behavior induced by nerve injury, but the cellular mechanism of this action remains unclear. Using the whole cell patch-clamp recording from rat’s spinal cord slices, we showed that superfusion of leptin...

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Détails bibliographiques
Auteurs principaux: Tian, Yinghong, Wang, Shuxing, Ma, Yuxin, Lim, Grewo, Kim, Hyangin, Mao, Jianren
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098907/
https://ncbi.nlm.nih.gov/pubmed/21376468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2011.01.054
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